Biologic markers in immunotoxicology

Introduction

The structure and function of the immune system and mechanisms of immunotoxicity

Biologic markers for immune-mediated disease

Autoimmune diseases

The capacity of toxic agents to compromise the immune system (biologic markers of immunosuppression)

Animal models for use in detecting immunotoxic potential and determining mechanisms of action

Human immune-system biologic markers of immunotoxicity

Application of biologic markers of immunotoxicity in epidemiology

Use of biologic markers in controversial areas of environmental health

Summary and recommendations.